A British court has rejected the final appeal from the parents of little Alfie Evans, whose life support will be shut off soon by a children’s hospital despite their objections.

Alfie suffers from a rare neurological disease that doctors at the hospital have been unable to treat. Alfie’s parents want to take him to a hospital in Italy that has offered to provide care and treatment and to do their best to combat the medical condition, but doctors at Alder Hey Children’s Hospital in London say Alfie’s condition is too far gone and they want to pull his life support and end his life.